TABLE 2.
Sensitivity of the ICT for the detection of different carbapenemases directly from Mueller-Hinton agar
| Inoculum (μl)a | Carbapenemase detectedb |
|||||
|---|---|---|---|---|---|---|
| OXA-48 like |
KPC |
NDM |
||||
| Sensitivity (% [no. detected/total no.]) | 95% CI (%) | Sensitivity (% [no. detected/total no.]) | 95% CI (%) | Sensitivity (% [no. detected/total no.]) | 95% CI (%) | |
| 1 (no AB) | 100 (25/25) | 86.3–100 | 100 (10/10) | 69.2–100 | 94.4 (17/18) | 72.7–99.9 |
| 10 (no AB) | 100 (25/25) | 86.3–100 | 100 (10/10) | 69.2–100 | 100 (18/18) | 81.5–100 |
| 1 EPM | 100 (25/25) | 86.3–100 | 100 (10/10) | 69.2–100 | 100 (18/18) | 81.5–100 |
| 1 IPM | 100 (25/25) | 86.3–100 | 100 (10/10) | 69.2–100 | 100 (18/18) | 81.5–100 |
| 1 MER | 100 (25/25) | 86.3–100 | 100 (10/10) | 69.2–100 | 100 (18/18) | 81.5–100 |
a
no AB, inoculum taken distant from antibiotic disk, with all others harvested next to an antibiotic disk; EPM, ertapenem; IPM, imipenem; MER, meropenem.
b
95% CI, 95% confidence interval.