TABLE 4.
Logistic regression analysis of the relationship between MIRU-VNTR genotypic clustering, as revealed by universal genotyping, and whether an isolate was originally requested for genotyping to confirm or refute transmission
| Characteristic | Clustereda vs unique OR (95% CI) |
|
|---|---|---|
| Unadjusted | Adjusted | |
| Requested | ||
| Yes | 4.6 (3.3–6.5) | 2.3 (1.5–3.3) |
| No | Reference | Reference |
| Age, yr | ||
| 0–34 | Reference | Reference |
| 35–54 | 1.7 (1.2–2.5) | 1.5 (1.0–2.3) |
| 55–74 | 0.9 (0.6–1.4) | 1.0 (0.6–1.5) |
| 75+ | 0.5 (0.3–0.8) | 0.8 (0.5–1.3) |
| Gender | ||
| Male | 1.3 (1.0–1.7) | 1.1 (0.8–1.5) |
| Female | Reference | Reference |
| Birthplace | ||
| Canada | 8.8 (6.2–12.3) | 5.3 (3.5–7.8) |
| Outside Canada | Reference | Reference |
| No. of risk factorsb | ||
| 0 | Reference | Reference |
| ≥1 | 6.6 (4.2–10.2) | 1.8 (1.0–3.0) |
a
A cluster is ≥2 patients with the same genotype by 24-locus MIRU-VNTR genotyping.
b
The risk factors are HIV, drug use, and alcohol misuse.