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. 2018 Apr 25;56(5):e01782-17. doi: 10.1128/JCM.01782-17

TABLE 2.

Summary of all results for the 323 patients tested both by T. pallidum PCR and by serology

Pattern of results and no. of samples Result by:
Serologya
PCR
CMIA TPPA RPR Consensusb T. pallidum HSV-1 HSV-2
T. pallidum PCR positive,  serology positive
    1 Pos Pos NR Pos Pos N/P N/P
    3 Pos Pos NR Pos Pos Neg Neg
    11 Pos Pos Pos Pos Pos N/P N/P
    39 Pos Pos Pos Pos Pos Neg Neg
    7 Pos Pos Pos Pos Pos Neg Pos
T. pallidum PCR positive,  serology negative (2) Neg N/P N/P Neg Pos Neg Neg
T. pallidum PCR  negative, serology  positive
    2 Pos Pos NR Pos Neg N/P N/P
    4 Pos Pos NR Pos Neg Neg Neg
    7 Pos Pos Pos Pos Neg N/P N/P
    17 Pos Pos Pos Pos Neg Neg Neg
T. pallidum PCR  negative, serology  negative
    42 N/A N/A N/A Neg Neg N/P N/P
    119 N/A N/A N/A Neg Neg Neg Neg
    15 N/A N/A N/A Neg Neg Pos Neg
    53 N/A N/A N/A Neg Neg Neg Pos
    1 N/A N/A N/A Neg Neg Pos Pos
a

CMIA, chemiluminescence immunoassay; TPPA, Treponema pallidum particle agglutination; RPR, rapid plasma reagin; Pos, positive; Neg, negative; NR, nonreactive; N/P, not performed; N/A, not applicable (syphilis serology was assessed as negative due to a nonreactive CMIA, or serology that was reactive but unchanged from a previous test result).

b

Syphilis serology assessed as positive or negative based on previous results.