Skip to main content
. 2018 Mar 12;33(5):895–904. doi: 10.1093/humrep/dey050

Table II.

Effects of bisphenol A on chromosome alignment in bovine metaphase II oocytes.

Ctrl fM (10−15 M) pM (10−12 M) nM (10−9 M) uM (10−6 M)
1 10 100 1 10 100 1 10 100 50
Aligned 190 (90.0) 30 (83.3) 33 (75.0) 72 (83.7) 27 (87.1) 36 (90.0) 19 (95.0) 43 (82.7) 85 (68.5) 54 (81.8) 39 (69.6)
Most aligned 11 (5.2) 2 (5.6) 3 (6.8) 4 (4.7) 2 (6.5) 2 (5.0) 0 (0.0) 3 (5.8) 12 (9.7) 3 (4.5) 8 (14.3)
Dispersed 10 (4.7) 4 (11.1) 8 (18.2) 10 (11.6) 2 (6.5) 2 (5.0) 1 (5.0) 6 (11.5) 27 (21.8) 9 (13.6) 9 (16.1)
P value 1.0000 0.0434 0.5953 1.0000 1.0000 1.0000 0.8913 <0.0001 0.3102 0.0044

The number of oocytes (percentage in parentheses) with aligned chromosomes, mostly aligned chromosomes and dispersed chromosomes are shown from at least three independent experiments per concentration. P values < 0.05 indicate a significant difference compared to control as determined by Fisher’s exact test.