Table IV.
Effects of bisphenol S on chromosome alignment in bovine metaphase II oocytes.
| Ctrl | fM (10−15 M) | pM (10−12 M) | nM (10−9 M) | uM (10−6 M) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 10 | 100 | 1 | 10 | 100 | 1 | 10 | 100 | 50 | ||
| Aligned | 85 (93.4) | 24 (96.0) | 9 (56.3) | 27 (90.0) | 17 (81.0) | 30 (81.1) | 18 (64.3) | 16 (80.0) | 17 (70.8) | 24 (77.4) | 19 (70.4) |
| Most aligned | 3 (3.3) | 1 (4.0) | 3 (18.8) | 2 (6.7) | 4 (19.0) | 5 (13.5) | 0 (0.0) | 2 (10.0) | 1 (4.2) | 0 (0.0) | 1 (3.7) |
| Dispersed | 3 (3.3) | 0 (0.0) | 4 (25.0) | 1 (3.3) | 0 (0.0) | 2 (5.4) | 10 (35.7) | 2 (10.0) | 6 (25.0) | 7 (22.6) | 7 (25.9) |
| P value | – | 1.0000 | 0.0013 | 1.0000 | 0.1035 | 0.3065 | <0.0001 | 0.4971 | 0.0131 | 0.0136 | 0.0079 |
The number of oocytes (percentage in parentheses) with aligned chromosomes, mostly aligned chromosomes, and dispersed chromosomes are shown from at least three independent experiments per concentration. P values < 0.05 indicate a significant difference compared to control as determined by Fisher’s exact test.