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. 2018 Mar 1;293(17):6470–6481. doi: 10.1074/jbc.RA117.001390

Figure 4.

Figure 4.

SDG-CW undergoes conformational change upon binding to H3K4me1. A, superimposition of SDG8-CW in apo form (salmon) and SDG8-CW (green) in complex with H3K4me1 peptide (yellow). B, a stereoview of the conformational change at SDG8-CW η1 turn due to H3K4me1 peptide binding. Key residues involved in binding are shown in sticks. C, superimposition of the aromatic cage of SDG8-CW in apo form and in complex with H3K4me1 peptide. D, surface representation of the aromatic cage of SDG8-CW in apo form with residues shown in sticks. E, conformational change at SDG8-CW C-terminal α-helix due to H3K4me1 peptide binding.