Table 1.

Correlations between antibodies and complement fixation to CSP among malaria-exposed PNG adults (n = 30)

Antibody	Rho C1q	Rho C4	Rho C2	Rho C3	Rho C5b-C9
IgG	0.831 (0.666 to 0.919)	0.813 (0.625 to 0.912)	0.797 (0.606 to 0.901)	0.831 (0.666 to 0.919)	0.803 (0.616 to 0.904)
IgG1	0.829 (0.662 to 0.917)	0.839 (0.672 to 0.925)	0.830 (0.664 to 0.918)	0.895 (0.784 to 0.950)	0.745 (0.518 to 0.874)
IgG2	0.607 (0.276 to 0.809)	0.443 (0.046 to 0.720)	0.404 (0.008 to 0.691)	0.552 (0.198 to 0.779)	0.485 (0.108 to 0.740)
IgG3	0.792 (0.592 to 0.900)	0.795 (0.586 to 0.904)	0.788 (0.585 to 0.898)	0.801 (0.608 to 0.905)	0.754 (0.527 to 0.880)
IgG4	0.416 (0.039 to 0.689)	–	–	–	–
IgM	0.826 (0.656 to 0.916)	0.655 (0.363 to 0.830)	0.620 (0.325 to 0.805)	0.738 (0.506 to 0.870)	0.791 (0.596 to 0.898)

Spearman’s correlation coefficient (rho) and 95% CI between anti-CSP antibodies and complement fixation to CSP. Values greater than 0.7 are underlined. Only significant correlations (p < 0.05) are shown

CI confidence interval, CSP circumsporozoite protein, PNG Papua New Guinea