Skip to main content
. 2018 Apr 30;16:63. doi: 10.1186/s12916-018-1057-z

Table 3.

Comparison of some key characteristics of implementation science and complexity science and their integration

Features Implementation science Complexity science Complexity science and implementation science
Task The task is specific: getting evidence into clinical practice in an understandable way The task is context dependent; properties of complexity apply to biology, ecology, physics, computer science, human social systems Tailored solutions and iterative processes
Theoretical assumptions Heterogeneous and diverse – numerous theories, frameworks, and models Homogenous – core assumptions of complexity science are characterized by ‘universality’ (i.e., they apply across all complex systems) Different theories, frameworks, and models require an understanding of complexity features such as unpredictability, uncertainty, emergence, interconnection
The intervention To be standardized to permit generalizability To be adapted to meet needs Factoring in complex interventions and complex settings
The context Full of confounders, a ‘problem’ to be solved for successful implementation An intrinsic part of a complex system; a dynamic environment that must be factored in for any intervention to be successfully taken up For improvement to be realized, the context must be re-etched or re-inscribed such that its culture, politics, and characteristics are altered
Historical underpinnings Evidence-based practice movement, statistics, and the scientific method Systems theory, chaos theory; emanating from diverse scientific disciplines More sophisticated change models can be encouraged to arise over time
Aims within health services research - Describing or guiding the process of translating research into practice (process models)
- Understanding or explaining what influences implementation outcomes (determinant frameworks, classic theories, implementation theories)
- Evaluating implementation (evaluation frameworks)
- Description of complex system
• Understanding context
• Relationships among agents
• Dynamics
• How rules and governance structures emerge, i.e., self-organization
- For prediction rather than implementation
- Ensure that turning evidence into practice is accomplished without too many unintended negative consequences; improvement might be sustained, potentially through the adaptation of the intervention to different settings
- Implementation is not merely based on effective planning but anticipation of a range of possible outcomes
Tools and methods Randomized controlled trials, behavior change interventions, step-wedge designs Causal loop diagrams, system dynamics modelling, network articulations Realist evaluation, long-term case study, participatory research, stakeholder analysis, systems mapping, social network analysis

Sources: Authors’ conceptualizations and May et al. [24]; Braithwaite et al. [7]; Rapport et al. [65]; Hawe et al. [32]