Table 1.

Criteria and examinations performed for the diagnosis of acute cystitis

Examination type	Criteria
Focused medical history exploration and standard urological physical examination (performed under conditions of clinical practice)	history of lower urinary tract symptoms (dysuria, frequency and urgency, suprapubic pain, hematuria, cloudy/foul smelling urine), exclusion of asymptomatic bacteruria absence of vaginal discharge or irritation no risk factors for complicated urinary tract infections no signs of acute pyelonephritis, absence of fever, systemic symptoms or flank pain
Microscopy of centrifuged urine sediment or urine dipstick test (mid-stream clean catch urine samples)	Sediment examination: at least one of the following conditions had to be true: 6 or more leucocytes per unit/high power field (HPF) 100 or more bacteria per unit/HPF 3 or more red blood cells per unit/HPF in urine sediment OR Urine dipstick test suggesting urinary tract infection (nitrite, leukocyturia, haematuria)
Urine culture (mid-stream clean catch urine samples)	103 or more CFU of uropathogens in 1 ml of unspun urine
Additional examinations, if indicated, to exclude other conditions than acute uncomplicated cystitis	In the case of atypical symptoms the physician in charge (expert urologist specialist) decided if additional diagnostic studies were necessary: kidney and bladder ultrasound kidney-ureter-bladder x-ray other clinical and/or instrumental diagnostic procedures and tests