Table.

Key Components of Patient-Centered Outcomes Research in Cardiovascular Imaging

Methodological considerations for randomized trials and observational research

PROs (eg, angina, functional status)

Assessment of benefits and risks (ie, safety, radiation exposure)

Maintenance of representative sampling for targeted priority population subgroups

Really informed consent, individualized

Effectiveness

Clinically representative indications for cardiovascular imaging

Meaningful effect size

Heterogeneity of effectiveness

“Given my characteristics, conditions, and preferences…”*

Patient-scientist collaborations

Transparent involvement for setting priorities, proposal development, and valuation of the findings

PRO indicates patient-reported outcome.

^*Adapted from the Patient-Centered Outcomes Research Institute.⁸³