Fig 1.

Timeline of signal and detector advances in the history of radionuclide myocardial perfusion imaging and accuracy of current techniques. (A) Time points of initial recognition that the electrocardiogram (ECG) and radiotracers provide diagnostic information for myocardial perfusion and metabolism. (B) Time span of use of detection modalities in cardiac stress testing. (C) Diagnostic information provided by stress testing as change from pretest to post-test likelihood of angiographically confirmed CAD. Reproduced with permission from the Journal of Nuclear Medicine, © by the Society of Nuclear Medicine and Molecular Imaging.⁶