Figure 4.
Enhanced human cell numbers in the PB of transplanted SRG-W41 versus NRG mice. Kinetics of human cell numbers in the PB of the irradiated female (A), irradiated male (B), non-irradiated female (C), and non-irradiated male (D) mice described in Figure 3. Results in SRG-W41 mice are again shown by the red symbols and for the NRG mice in black. Numbers of human CD45+, GM, and B-lymphoid cells and platelets per milliliter of recipient blood were determined 3, 6, 10, 20, and 30 weeks after transplantation. Circles and triangles indicate female and male mice, respectively. Asterisks indicate statistical significance (*p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001).