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Physiological reaction for nucleotide synthesis by PfHGXPRT. The reaction is a freely reversible Mg2+-dependent conversion of 6-oxopurine bases to their respective nucleoside monophosphates and inorganic pyrophosphate (PPi), with the phosphoribosyl group being derived from 5-phospho-α-D-ribosyl 1-pyrophosphate (PRPP).
