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. Author manuscript; available in PMC: 2018 Apr 30.
Published in final edited form as: Biochemistry. 2017 Nov 21;56(48):6368–6376. doi: 10.1021/acs.biochem.7b01027

Figure 2.

Figure 2

Enzymatic synthesis of isotopically labeled PRPP from glucose or ribose. The final product of the first synthesis reaction is ATP, which is subsequently converted to AMP. Isotopically labeled PRPP is produced in the final synthesis step and used as soon as possible following isolation.