Fig. 2.

Baseline noncontrast T1WI (A), CE-T1WI (B), mIP SWI (C), and 2-week followup noncontrast T1WI images (D) of a patient treated with anti-toxoplasma medication. Two weeks later, the lesion in the left temporal lobe and a lesion in the left cerebellum (not shown) developed speckled intrinsic hyperintense foci on noncontrast T1WI (white arrowheads on A and D), a consequence that occurs in response to protein hydration layers that fill up the cytoplasm of reactive astrocytes. Two susceptibility signal foci (black arrowheads on D) are shown in the left temporal lobe lesion. While the SWI signal abnormalities remained stable on followup, the unusual T1-hyperintense signal changes was a transitory condition detected after empiric anti-toxoplasma therapy on most patients with toxoplasmosis.