Figure 2. The M-MDSC population is expanded in the peripheral blood of CRC patients.

See also Supplemental Figure 1. (A) Peripheral blood mononuclear cells (PBMCs) from colorectal cancer (CRC) patients and healthy donors (HD) were subjected to immunophenotyping by flow cytometry. Analysis of 1 representative sample is shown. (B) The frequency of M-MDSCs (CD14⁺HLA-DR^lo) and PMN-MDSCs (low-density CD14^–CD11b⁺CD15⁺) in the live subset of PBMCs. Gray dots represent individual values; black squares, mean values. Statistical data are presented in Table 3.