Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Apr 27;12:997–1008. doi: 10.2147/DDDT.S151029

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Ju et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Effects of 4-amino-2-trifluoromethyl-phenyl retinate (ATPR) on proliferation of MCF-7 cells after silencing of CRABP2.

Notes: (A) Immunofluorescence staining on MCF-7 cells confirms significant reduction of CRABP2 expression in the CRABP2-siRNA group. Representative images obtained with a 200× objective. (B) An MTT assay was performed to evaluate transfected MCF-7 cells that were untreated or treated with 1 × 10⁻⁶ mol/L ATPR for 24, 48, and 72 h. *P < 0.05, ***P < 0.001. For 48 h, ATPR(−) siRNA(−) vs ATPR(+) siRNA (one-way ANOVA, P < 0.001), ATPR(+) negative siRNA(+) vs ATPR(+) CRABP2 siRNA(+) (one-way ANOVA, P = 0.048). For 72 h, ATPR(−) siRNA(−) vs ATPR(+) siRNA (one-way ANOVA, P < 0.001), ATPR(+) negative siRNA(+) vs ATPR(+) CRABP2 siRNA(+) (one-way ANOVA, P = 0.034).