Table 3.
Single regression analysis of plasma GDF11 in COPD patients
| Variables | GDF11
|
|
|---|---|---|
| β* | p-value | |
| Age (years) | −0.33 | 0.611 |
| Smoking | −0.06 | 0.576 |
| FVC % predicted | 0.64 | <0.001 |
| FEV1 % predicted | 0.43 | <0.001 |
| IC | 0.66 | <0.001 |
| DLco’ % predicted | 0.31 | 0.001 |
| 6MWD | 0.48 | <0.001 |
| Number of steps | 0.28 | <0.001 |
| IL-6 | −0.21 | 0.020 |
| QMVC % predicted | 0.64 | <0.001 |
Notes:
*
β = regression coefficient. All data were log transformed. Data were analyzed by single linear regression analysis.
Abbreviations: DLco’, diffusing capacity of the lung for carbon monoxide; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; GDF11, growth differentiation factor 11; IC, inspiratory capacity; IL-6, interleukin-6; 6MWD, 6-minute walking distance; QMVC, quadriceps maximal voluntary contraction.