Table 1.
Characteristics of all patients
| Characteristics | I+C (group A, n=59) | I (group B, n=75) | C (group C, n=57) | Total (n=191) |
|---|---|---|---|---|
| Median age (years) | 62.0 | 60.6 | 59.9 | 60.8 |
| Sex | ||||
| Male | 40.7% (n=24) | 37.3% (n=28) | 47.4% (n=27) | 41.4% (n=79) |
| Female | 59.3% (n=35) | 62.7% (n=47) | 52.6% (n=30) | 58.6% (n=112) |
| Smoking history | ||||
| Nonsmoker | 61.0% (n=36) | 65.3% (n=49) | 59.6% (n=34) | 62.3% (n=119) |
| Smoker | 39.0% (n=23) | 34.7% (n=26) | 40.4% (n=23) | 37.7% (n=72) |
| ECOG performance status score | ||||
| 0–1 | 100% (n=59) | 96.0% (n=72) | 98.2% (n=56) | 97.9% (n=187) |
| 2 | 0% (n=0) | 4.0% (n=3) | 1.8% (n=1) | 2.1% (n=4) |
| Type of EGFR mutation | ||||
| Exon 19 deletion | 52.5% (n=31) | 56.0% (n=42) | 50.9% (n=29) | 53.4% (n=102) |
| L858R | 47.5% (n=28) | 44.0% (n=33) | 49.1% (n=28) | 46.6% (n=89) |
| Histologic diagnosis | ||||
| Adenocarcinoma | 100% | 100% | 100% | 100% |
Abbreviations: C, chemotherapy; ECOG, Eastern Cooperative Oncology Group; EGFR, epidermal growth factor receptor; I, icotinib; I+C, icotinib+chemotherapy.