Table 5.
Short-term curative effects of patients with EGFR 19 exon deletion
| Curative effects | I+C (group A1, n=31) | I (group B1, n=42) | C (group C1, n=29) |
|---|---|---|---|
| Best response | |||
| CR | 3.2% (n=1) | 0% (n=0) | 0% (n=0) |
| PR | 71.0% (n=22) | 50.0% (n=21) | 24.1% (n=7) |
| SD | 22.6% (n=7) | 42.9% (n=18) | 44.8% (n=13) |
| PD | 3.2% (n=1) | 7.1% (n=3) | 31.0% (n=9) |
| ORR (%) | 74.2 | 50.0 | 24.1 |
| DCR (%) | 96.8 | 92.9 | 69.0 |
Abbreviations: C, chemotherapy; CR, complete remission; DCR, disease control rate; EGFR, epidermal growth factor receptor; I, icotinib; I+C, icotinib+chemotherapy; ORR, overall response rate; PD, progression disease; PR, partial disease; SD, stable disease.