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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Comput Biol Med. 2016 Jun 25;92:156–167. doi: 10.1016/j.compbiomed.2016.06.026

Fig. 6.

Fig. 6

Reference volume for a typical composition of tissue. The domain includes extracellular space, cell membranes and cell interior. Boundary conditions: Concentrations at inlet outlet are increased from zero to 1M with small concentration gradient, while there is no flux though lateral surfaces. (a) Concentration field in the RV and graph of concentration along a line AB. (b) Mass release curve. (c) Diffusion coefficient for the equivalent homogenous continuum. Model size: 34,000 2D finite elements, 1684 fictitious 1D element, 34,281 nodes.