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. 2018 Apr 30;13(4):e0196626. doi: 10.1371/journal.pone.0196626

Fig 4. Involvement of β-AR subtypes, adenylyl cyclase and PKA in post-translational modifications of NF2.

Fig 4

(A) ARVMs in CGP+ISO, ICI+ISO and H89+ISO groups were pretreated with CGP, ICI and H89, respectively, for 30 min prior to ISO treatment for 15 min. (B) ARVMs were treated with forskolin (FSK), an adenylyl cyclase activator, for 15 min. Cell lysates were analyzed by western blot using phospho-specific anti-NF2 antibodies. The lower panels exhibit the mean data normalized to GAPDH. *p<0.05 vs. CTL; $p<0.05 vs. ISO; n = 6–9.