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. 2018 Apr 18;12(4):e0006420. doi: 10.1371/journal.pntd.0006420

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© 2018 Gunaratne et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Changes in tension measured in mouse mesenteric artery vessel strips evoked by KPSS (left, arrow), ±PZQ (circle, 100μM) added at basal tone (middle) and KPSS (arrow) followed by addition of ±PZQ to a contracted vessel (purple circle and trace, right). Solution exchanges to physiological saline shown as ‘w’ (wash). (B) Dose-response relationship quantifying peak relaxation evoked by indicated concentrations of ±PZQ. (C) Effect of repeated additions of ±PZQ (10μM, black circles) without solution exchange on contractile tone in a vessel contracted by solution exchange to KPSS (arrow).