Figure 3.

TSLP-mediated effects on metastasis are independent of the adaptive immune system. (A) Primary tumor growth of the indicated cell population in SCID mice, as in Fig. 1 (n = 15 per group). (B) Quantification of spontaneous lung metastasis of the indicated cell population at endpoint tumor volumes in A (n = 15 per group). (C) Experimental lung metastasis in SCID mice, as in Fig. 2 (n = 9-10 per group). (D and E) Similar to A and B, except that tumor growth studies were performed in athymic mice (n = 9-10 per group). Each line or data point represents results from an individual mouse; compilation of 2 independent experiments in all panels. **P < 0.01; ***P < 0.001; ns, P > 0.1.