. Author manuscript; available in PMC: 2018 Apr 30.

Published in final edited form as: J Clin Psychiatry. 2017 Mar;78(3):e234–e243. doi: 10.4088/JCP.15m09815

Table 6.

a.: Association between SLES and parent group, parent responses
		BP	Non-BP	Healthy Control	Neg-Bin GLMM		Pairwise Comparisons p-values

		N=269	N=88	N=81	Chi-sq	p-value	BP vs. Non- BP	BP vs. HC	non-BP vs. HC
		m (se) ^a	m (se) ^a	m (se) ^a

	Total # of events	11.39 (0.04)	9.80 (0.07)	6.52 (0.08)	36.82	<0.0001^*	0.0795	<0.0001	0.0002
	# of events with effect = 4	3.45 (0.09)	2.32 (0.16)	1.33 (0.17)	25.4	<0.0001^*	0.0261	<0.0001	0.0184
	# of events with effect >= 3	6.64 (0.06)	5.49 (0.11)	2.81 (0.13)	37.45	<0.0001^*	0.1394	<0.0001	<0.0001
	Severity	0.68 (0.10)	0.51 (0.18)	0.25 (0.25)	14.23	0.0008^*	0.1618	0.0003	0.0255
	Independent	6.11 (0.05)	5.16 (0.08)	3.32 (0.09)	37.1	<0.0001^*	0.0633	<0.0001	0.0002
	Uncertain	1.92 (0.06)	1.93 (0.10)	1.10 (0.13)	16.13	0.0003^*	0.975	0.0001	0.0009
	Dependent	3.29 (0.06)	2.64 (0.11)	2.05 (0.12)	13.3	0.0013	0.0791	0.0005	0.1198
	Negative	9.32 (0.05)	8.08 (0.08)	5.57 (0.08)	29.04	<0.0001^*	0.1097	<0.0001	0.0012
	Neutral	1.64 (0.07)	1.40 (0.12)	0.72 (0.16)	23.07	<0.0001^*	0.2516	<0.0001	0.001
Event Count	Positive Count(%)^b	75 (30)	15 (17.1)	20 (24.7)	chisq = 5.77	p-value = 0.06

	Severe	2.30 (0.13)	1.82 (0.22)	0.74 (0.25)	15.66	0.0004	0.3661	<0.0001	0.0084
	Independent	16.50 (0.05)	13.42 (0.09)	7.54 (0.10)	48.37	<0.0001^*	0.0544	<0.0001	<0.0001
	Uncertain	5.68 (0.07)	5.42 (0.12)	3.04 (0.13)	18.09	0.0001^*	0.7313	<0.0001	0.0012
	Dependent	9.48 (0.08)	6.88 (0.13)	5.30 (0.14)	15.32	0.0005	0.0325	0.0002	0.168
	Negative	26.11 (0.05)	21.80 (0.09)	13.81 (0.09)	34.58	<0.0001^*	0.0822	<0.0001	0.0005
	Neutral	4.59 (0.08)	3.71 (0.14)	1.49 (0.16)	40.41	<0.0001^*	0.1808	<0.0001	<0.0001
Total Effect	Positive	0.90 (0.15)	0.48 (0.27)	0.68 (0.27)	4.38	0.112

b.: Association between SLES and current pathology, parent responses
		Current Any Axis I			Current MDE			Current ADHD			Current DBD			Current SUD			Current Anxiety

		Odds Ratio^*	t stat	p-value	Odds Ratio ^a	t stat	p-value	Odds Ratio^*	t stat	p-value	Odds Ratio ^a	t stat	p-value	Odds Ratio^*	t stat	p-value	Odds Ratio ^a	t stat	p-value

	total # of events	1.10369	5.43	<0.0001^*	1.062389	2.91	0.0039	1.03975	2.56	0.0115	1.08912	4.85	<0.0001^*	1.10838	4.02	<0.0001^*	1.03263	2.14	0.0341
	# of events with effect = 4	1.18875	5.16	<0.0001^*	1.184712	4.43	<0.0001^*	1.04979	1.66	0.0992	1.08807	2.96	0.0033	1.15269	3.56	0.0004^*	1.13701	4.42	<0.0001^*
	# of events with effect >= 3	1.12908	5.43	<0.0001^*	1.113825	4.15	<0.0001^*	1.03905	1.93	0.0551	1.05919	2.96	0.0033	1.1284	4.4	<0.0001^*	1.06669	3.36	0.001^*
	Independent	1.11952	3.89	0.0002^*	1.069381	1.56	0.1203	1.05096	1.77	0.0783	1.1031	3.34	0.0009	1.18258	3.79	0.0002^*	1.04889	1.72	0.0885
	Uncertain	1.48216	5.4	<0.0001^*	1.289688	2.24	0.0257	1.24321	2.97	0.0035	1.4579	4.72	<0.0001^*	1.68035	4.01	0.0001^*	1.15073	1.94	0.054
	Dependent	1.27724	5.57	<0.0001^*	1.237632	3.88	0.0001^*	1.10893	2.65	0.009	1.29719	5.76	<0.0001^*	1.29033	4.03	<0.0001^*	1.0854	2.13	0.035
	Negative	1.12131	5.47	<0.0001^*	1.080399	3.05	0.0024^*	1.04677	2.54	0.0124	1.10098	4.72	<0.0001^*	1.13906	4.28	<0.0001^*	1.04263	2.33	0.0211
	Neutral	1.25571	3.25	0.0015	1.107716	0.85	0.395	1.15431	2.02	0.0455	1.36602	3.98	<0.0001	1.26934	2.22	0.0285	1.06061	0.81	0.4194
Count	Positive	1.73429	2.3	0.0233	3.227152	2.59	0.0099	1.23479	0.72	0.472	2.10665	2.55	0.0113	5.03544	3.01	0.0031	1.05488	0.18	0.8544

	Independent	1.04152	4.04	<0.0001^*	1.030485	1.95	0.0519	1.02052	1.98	0.0503	1.03277	3.08	0.0022	1.07024	4.16	<0.0001^*	1.02654	2.55	0.0121
	Uncertain	1.14294	5.51	<0.0001^*	1.129189	3.17	0.0016^*	1.06426	2.47	0.0147	1.11505	4.19	<0.0001^*	1.21179	4.39	<0.0001^*	1.05759	2.26	0.0254
	Dependent	1.07914	5.25	<0.0001^*	1.078251	4.29	<0.0001^*	1.02542	1.92	0.0573	1.06607	4.76	<0.0001^*	1.08965	4.46	<0.0001^*	1.03846	2.96	0.0037
	Negative	1.03765	5.35	<0.0001^*	1.031228	3.47	0.0006^*	1.01407	2.23	0.0275	1.02751	4.26	<0.0001^*	1.05209	5.15	<0.0001^*	1.02004	3.18	0.0019
	Neutral	1.08904	3.4	0.0009	1.070633	1.83	0.068	1.04739	1.77	0.0793	1.09986	3.55	0.0004	1.10672	2.33	0.0216	1.04324	1.63	0.1063
Total Effect	Positive	1.21046	2.5	0.0137	1.444264	2.82	0.005	1.02623	0.28	0.7806	1.1474	1.48	0.1386	1.45107	2.46	0.0152	1.07873	0.86	0.394

Standard errors are in log scale.

Occurrence of positive event was modeled differently.

Significant after multivariate adjustment and FDR correction

Controlling for parent group only

Significant at 0.05 level after mulitvariate adjustment and FDR correction