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. Author manuscript; available in PMC: 2018 Apr 30.
Published in final edited form as: J Med Chem. 2016 Mar 28;59(7):3140–3151. doi: 10.1021/acs.jmedchem.5b01912

Table 4.

FIC Values of 3 and Antibiotics AMP, NOR, and KAN As Determined by the Checkerboard Method

ΣFICa
S. aureus RN4220 P. aeruginosa PAO1
ampicillin 0.75 2.0
norfloxacin 0.75   0.75
kanamycin 0.25   0.75
a

ΣFIC, combined fractional inhibitory concentration. The formula for calculating the ΣFIC is described in the Experimental Section.