Table 3.

QALY Weights and Costs

	Mean	Source
QALY weights
Healthy	1	22
Healthy, with past treatment (non-MDR or MDR)	0.942	16
Latent DS TB	1	22
Latent MDR TB	1	22
Latent with past treatment (non-MDR or MDR)	0.942	16
Active DS TB	0.663	17
Active DS TB in RNTCP Cat I	0.843	32
Active DS TB in RNTCP Cat II	0.843	32
Active MDR TB	0.663	17
Active MDR TB in RNTCP Cat I	0.663	17
Active MDR TB in RNTCP Cat II	0.663	17
Active MDR TB in RNTCP Cat IV	0.753	*
Dead	0
Costs, in 2013 USD
Treatment Costs**
Public System
Nonmedical Public Clinic Patient Costs, Monthly	6.20	8
Fixed Costs
Sputum Smear Cost	4.89	18
DST cost	26.04	18
CAT I/III Monthly Costs
Drugs	3.53	11,19,20
Other Clinic Costs	31.08	33
CAT II Monthly Costs
Drugs	8.01	11,19,20
Other Clinic Costs	31.08	33
CAT IV Monthly Costs
Drugs, IP (first 6 months)	84.92	11,19,20
Drugs, CP (following 18 months)	67.50	11,19,20
Other Clinic Costs	31.08	33
Private System
Private Treatment Direct Costs, Monthly	68.18	8
Intervention Costs
PPM referral (includes per-person program & monitoring costs)	34.03	34
GeneXpert	18.30	18
Non-TB Health Related Costs
Monthly Per Person, Non-TB Health Expenses		23
Age	Males
0–9	0.20
10–19	0.17
20–29	1.20
30–39	1.59
40–49	1.62
50–59	2.48
60–69	3.25
70+	4.66

^*Average of no treatment and CAT I (effective treatment for MDR but toxic)

^**A full public clinic treatment regimen includes two sputum smears, one DST, and monthly drug and other clinic costs (sputum smears are replaced by DST in Cat IV) for total costs of 183.33, 264,97, and 3649.58 for category I, II, and IV treatment respectively. See Appendix Table S3 for details.