Figure 1.

shRNAs derived from 17 TS genes cause growth reduction in HeyA8 cells.

(A) Percent cell confluence over time of HeyA8 cells after infection with shScr, shL3 and two shRNAs for each of the 17 TS genes. The curves for cells infected with two independent shRNAs for each TS gene and their specific ID number and respective growth reduction caused by each shRNA are shown in blue and green. Percent growth reduction values (as shown in Table 1) were calculated using STATA1C software when cells infected with shScr reached half maximal confluency as indicated by the red dotted line. (B) Percent cell confluence over time of HeyA8 cells after infection with shScr, shL3, and five shRNAs targeting PTEN (left) and four shRNAs targeting p53 (right). Percent growth reduction values are shown in Table 1.