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Toxic shRNAs derived from eight TS genes induce DISE-like morphological changes in HeyA8 cells.
Representative phase-contrast images showing elongated cell shapes (A); enlarged, flattened cells and presence of intracellular granules in HeyA8 cells infected with shRNAs against eight of the 17 TS and shL3 (B). shScr treated cells are shown as control.
