Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Rsf-1 was a direct target of let-7a-5p. (A) The predicted let-7a-5p complementary site within the Rsf-1 3′-UTR and the mutated sites were shown. (B) let-7a-5p obviously repressed the luciferase activity of the pMIR-Rsf-1-Wt but not that of pMIR-Rsf-1-Mut. Upregulation of let-7a-5p decreased, but anta-let-7a-5p increased, the Rsf-1 mRNA level (C) and protein level (D) in 5–8F cells. ***P < 0.001.
