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. 2018 Jan 29;12(2):109–117. doi: 10.4161/19336918.2014.990781

Figure 4.

Figure 4.

MMP-9 was the key molecule for G-1 induced migration and invasion of RCC cells. ACHN cells were pretreated with inhibitors of MMP-2 (Sc-204092, 10 nM) and MMP-9 (Cat-444278, 10 nM) for 60 min and then stimulated with 1 μM G-1 for 48 h. The number of migrated (A) or invaded (B) cells were compared with the control. Data are presented as means ± SD of three independent experiments. *P < 0.05 compared with control; **P < 0.01 compared with control.