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. 2018 Feb 8;17(4):448–458. doi: 10.1080/15384101.2017.1395533

Figure 1.

Figure 1.

Effect of CTR1 in cervical cancer cell chemoresistance to DDP (A) HeLa and CaSki cells were transfected with si-CTR1; HeLa/DDP and CaSki/DDP cells were transfected with CTR1 vectors. CTR1 protein levels were verified using Western blot assays. (B)-(E) The cell viability of si-CTR1-transfected HeLa and CaSki cell upon 2 μg/ml DDP treatment and CTR1-transfected HeLa/DDP and CaSki/DDP cell upon 8 μg/ml DDP treatment was determined using MTT assays. (F)-(G) The DNA synthesis capability of si-CTR1-transfected HeLa and CaSki cell upon 2 μg/ml DDP treatment and CTR1-transfected HeLa/DDP and CaSki/DDP cell upon 8 μg/ml DDP treatment was determined using BrdU assays. The data are presented as mean ± SD of three independent experiments. *P<0.05, **P<0.01.