Table 3.
Multiple regression models of total and HMW adiponectin levels on change in HOMA measure at 6 months (N = 143).
| Models | Change in HOMA | R2 | Models | Change in HOMA | R2 | ||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||
| Estimate | s.e. | P | Estimate | s.e. | P | ||||
| Model 1 | Model 1 | ||||||||
| Adiponectin Δ (ug/ml) | −0.25 | 0.09 | 0.004 | 0.06 | HMW Δ (ug/ml) | −0.34 | 0.14 | 0.02 | 0.04 |
| Model 2 | Model 2 | ||||||||
| Adiponectin Δ (ug/ml) | −0.25 | 0.08 | 0.005 | 0.11 | HMW Δ (ug/ml) | −0.32 | 0.15 | 0.03 | 0.09 |
| Gender | 0.95 | 0.43 | 0.03 | Gender | 0.99 | 0.43 | 0.02 | ||
| Race | 0.38 | 0.29 | 0.20 | Race | 0.33 | 0.30 | 0.28 | ||
| Age (yr) | 0.01 | 0.01 | 0.9 | Age (yr) | 0.0003 | 0.01 | 0.98 | ||
| Model 3 | Model 3 | ||||||||
| Adiponectin Δ (ug/ml) | −0.26 | 0.09 | 0.003 | 0.16 | HMW Δ (ug/ml) | −0.34 | 0.15 | 0.02 | 0.14 |
| Gender | 0.64 | 0.43 | 0.14 | Gender | 0.68 | 0.44 | 0.12 | ||
| Race | 0.44 | 0.29 | 0.13 | Race | 0.38 | 0.29 | 0.19 | ||
| Age (yr) | −0.000 | 0.02 | 0.97 | Age (yr) | −0.001 | 0.02 | 0.92 | ||
| Baseline weight (kg) | −0.03 | 0.009 | 0.003 | Baseline weight (kg) | −0.03 | 0.009 | 0.003 | ||
| Model 4 | Model 4 | ||||||||
| Adiponectin Δ (ug/ml) | −0.17 | 0.08 | 0.04 | 0.27 | HMW Δ (ug/ml) | −0.18 | 0.14 | 0.21 | 0.26 |
| Gender | 0.06 | 0.42 | 0.88 | Gender | 0.10 | 0.48 | 0.82 | ||
| Race | 0.46 | 0.27 | 0.09 | Race | 0.40 | 0.27 | 0.14 | ||
| Age (yr) | 0.0005 | 0.01 | 0.97 | Age (yr) | 0.000 | 0.01 | 0.99 | ||
| Baseline weight (kg) | −0.03 | 0.009 | 0.005 | Baseline weight (kg) | −0.02 | 0.008 | 0.006 | ||
| Weight Δ (kg) | 0.10 | 0.02 | < 0.0001 | Weight Δ (kg) | 0.10 | 0.02 | < 0.0001 | ||
HMW=high molecular weight; HOMA= homoeostasis model assessment of insulin resistance; Δ=change.
Changes values were defined as 6 months - baseline.
Reference groups: gender-males, race- white