Fig. 6.

Overexpression of PA28α improves photoreceptor survival in Gγ₁^−/− mice. a Spider diagrams representing the number of photoreceptor nuclei in 100 μm segments of the inferior and superior retina at various distances from the optic nerve head. Data were collected from five mice at 3 months of age and shown as mean ± SD. Data points for which the difference in the number of nuclei between treated and untreated animals was statistically significant (p < 0.05) are shown as filled circles and those for which statistical significance was not achieved as open circles. b The total number of nuclei in all eight 100 μm retinal segments represented in spider diagrams of a. Data are shown as mean ± SEM. c Representative images of inferior retina cross-sections at the 1 mm distance from the optic nerve head; scale bar: 50 μm. Mouse genotypes are indicted above the panels. See Supplementary Fig. 9 for images of representative cross-sections through the entire retinas