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. 2018 Apr 24;9:669. doi: 10.3389/fimmu.2018.00669

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Copyright © 2018 Han, Jin, Zhou, Zhang, Fan, Dai, Lin, Huang, Xuan, Zhang and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The percentage of Treg and Th17 cell counts are associated with aGVHD and intestinal microbiota correlates with the Treg/Th17 balance. The phenotype of regular T cells (Treg) (A) and IL-17-producing T cells Th17 (B) in peripheral mononuclear blood cells was examined. The percentage of Treg (C) and Th17 (D) cells is shown for the two groups. Correlations between the relative abundance of microbiota and percentage of T subsets and the Treg/Th17 ratio (E1: Lachnospiraceae and Treg; E2: Lachnospiraceae and Th17; E3: Lachnospiraceae and Treg/Th17. F1: Ruminococcaceae and Treg; F2: Ruminococcaceae and Th17; F3: Ruminococcaceae and Treg/Th17; G1: Enterobacteriaceae and Treg; G2: Enterobacteriaceae and Th17; G3: Enterobacteriaceae and Treg/Th17).

The percentage of Treg and Th17 cell counts are associated with aGVHD and intestinal microbiota correlates with the Treg/Th17 balance. The phenotype of regular T cells (Treg) (A) and IL-17-producing T cells Th17 (B) in peripheral mononuclear blood cells was examined. The percentage of Treg (C) and Th17 (D) cells is shown for the two groups. Correlations between the relative abundance of microbiota and percentage of T subsets and the Treg/Th17 ratio (E1: Lachnospiraceae and Treg; E2: Lachnospiraceae and Th17; E3: Lachnospiraceae and Treg/Th17. F1: Ruminococcaceae and Treg; F2: Ruminococcaceae and Th17; F3: Ruminococcaceae and Treg/Th17; G1: Enterobacteriaceae and Treg; G2: Enterobacteriaceae and Th17; G3: Enterobacteriaceae and Treg/Th17).