Figure 7.

SF suppressed MPP⁺-mediated loss of Parkin and PTEN-induced putative kinase 1 (PINK1) in SH-SY5Y cells. Cells were exposed to 1 mM MPP⁺ for 24 h in the absence or presence of 0.01 mg/mL SF for 24 h, after which they were subjected to immunofluorescent staining using antibodies against Parkin and PINK1. MPP⁺ suppressed Parkin and PINK1 expression, while SF enhanced them. Scale bar = 50 μm. Values are the means ± SD (three slides per group). ^a–cMeans with different letters are significantly different (p < 0.05) by Duncan’s multiple-range test.