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. 2018 Apr 30;8:6763. doi: 10.1038/s41598-018-25154-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Drop test of S. cerevisiae cells on CSM medium containing test thiosulfinates at 5 µM. The wt BY4742 was compared with the Δyap1 and other mutants. Drops (10 µL) of serial dilutions up to 10⁻⁶ were plated out. In the control both wt and mutant cells behaved similarly and grew down to the 10⁻⁶ dilution. The effects of the various thiosulfinates are shown in the remaining panels.