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. 2018 Apr 24;9:115. doi: 10.3389/fgene.2018.00115

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Copyright © 2018 Nishino, Kochi, Shigemizu, Kato, Ikari, Ochi, Noma, Matsui, Morizono, Boroevich, Tsunoda and Matsui.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Estimated effect-size distributions, $\hat{π} \times \hat{g}$ , by derived allele frequency (DAF) bins. The upper panels (heatmap colors) for each GWAS results show $\hat{π} \times ĝ$ . The lower panels show means of $\hat{π} \times ĝ$ . (A) Rheumatoid arthritis (Asian). (B) Rheumatoid arthritis (European). (C) Coronary artery disease (CARDIoGRAM). (D) Coronary artery disease (C4D). (E) Schizophrenia. (F) Bipolar disorder.