Table 1.
Characteristics | Normal ABI ≥ 0.8 ≤ 1.3 | Low < 0.8 | High > 1.3 |
---|---|---|---|
Patient number | 249 | 46 | 65 |
Age Years | 63.3 ± 11.9 | 70.7 ± 8.7* | 70.5 ± 8.9* |
Male percent | 49.4 | 69.6 | 72.3 |
Duration of diabetes years | 11.7 ± 9.3 | 18.2 ± 12.1* | 18.4 ± 9.6* |
BMI kg/m2 | 29.5 ± 5.2 | 29.3 ± 5.0 | 31.7 ± 5.4*# |
Waist/height cm/m n |
61.9 ± 8.2 215 |
61.9 ± 6.9 30 |
66.7 ± 7.7*# 51 |
Hba1c percent | 7.7 ± 1.5 | 7.7 ± 1.3 | 8.1 ± 1.8 |
Hba1c mmol/mol | 61 ± 4.5 | 61 ± 8.3 | 65 ± 8.0 |
Total cholesterol mmol/L n |
4.3 ± 1.2 237 |
4.0 ± 1.2 45 |
4.0 ± 1.2 59 |
HDL mmol/L n |
1.2 ± 0.4 233 |
1.1 ± 0.3 36 |
1.2 ± 0.3 57 |
Triglycerides mmol/L n |
1.8 ± 1.2 233 |
1.9 ± 1.4 45 |
1.9 ± 1.1 59 |
eGFR mL/min/1.73 m2 | 76.4 ± 24.3 | 67.2 ± 18.8^ | 60.4 ± 28.5* |
eGFR 5 years prior mL/min/1.73 m2 | 80.1 ± 23.2 | 74.0 ± 19.6 | 70.5 ± 26.3^ |
Urine albumin/creatinine ratio mg/mmol n |
19.0 ± 83.4 210 |
25.5 ± 81.3* 34 |
23.2 ± 51.6 57 |
Calcium.phosphate product mmol/L.mmol/L n |
2.63 ± 0.53 211 |
2.87 ± 0.56^ 36 |
2.70 ± 0.44 59 |
Serum alkaline phosphatase mmol/L n |
74.2 ± 18.3 238 |
82.6 ± 24.9 44 |
79.9 ± 22.4## 63 |
25 hydroxy-vitamin D n |
61.1 ± 22.6 184 |
59.2 ± 18.3 32 |
49.2 ± 20.4* 51 |
Insulin use percent | 48.2 | 69.6 | 60 |
Statin use percent | 74.3 | 89.1^ | 90.8^ |
Hypertension percent | 75.5 | 97.8^ | 90.8^ |
Smoking% Never Current Prior |
58.4 12.2 29.4 |
27.3 20.5 52.3 |
50 3.4## 26.6 |
Coronary artery diseasepercent | 17.3 | 47.8^ | 30.8^ |
Stroke percent | 5.6 | 17.4^ | 13.8^ |
Foot Ulcer percent | 4.1 | 32.6^ | 16.9^ |
Osteomyelitis percent | 3.6 | 21.7^ | 12.3^ |
Lower limb Amputation percent | 0.8 | 10.9^ | 7.7^ |
Biothesiometer reading volts n |
30 ± 16 227 |
47 ± 16* 43 |
49 ± 17* 61 |
Diabetic retinopathy percent | 21 | 34.8^ | 41.9^ |
n = number available for analysis if less than complete set.
p < 0.01, as compared to normal ABI group.
p < 0.05, as compared to low ABI group.
p < 0.05 as compared to normal ABI group.
p < 0.05 across groups.