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Effect of DRDE-30 on bleomycin-induced changes in key fibrotic mediators. (A) BALF levels of the pro-fibrotic cytokine, TGF-β. Data represents mean ± SEM, n = 6 per group. (B) Changes in the protein expression of the EMT markers E-Cadherin and α-SMA as assessed by western blotting at 21 days post treatment. (C) Densitometry of target proteins after normalizing with β-actin. Results are expressed as mean ± SEM. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.
