Table 1.
Effect of DRDE-30 on bleomycin-induced changes in total and differential cell counts in the broncheoalveolar lavage fluid of mice.
| Group | Total cells (×105/ml) Day 06 | Total cells (×105/ml) Day 21 | Neutrophils (×105/ml) Day 06 | Macrophages (×105/ml) Day 06 | Lymphocytes (×105/ml) Day 06 |
|---|---|---|---|---|---|
| Control | 4.35 ± 2.56 | 0.85 ± 0.43 | 0.2259 ± 0.02 | 4.656 ± 0.23 | 0.8469 ± 0.04 |
| DRDE-30 | 6.03 ± 0.26 | 1.59 ± 0.42 | 0.2338 ± 0.03 | 4.404 ± 0.24 | 0.8649 ± 0.04 |
| BLM | 22.47 ± 3.09∗∗∗ | 13.33 ± 0.3∗∗∗ | 7.297 ± 0.76∗∗∗ | 11.73 ± 0.72∗∗∗ | 5.733 ± 0.35∗∗∗ |
| DRDE-30+B | 11.80 ± 0.6### | 6.23 ± 1.25## | 3.561 ± 0.65## | 8.436 ± 0.34## | 3.178 ± 0.42### |
Data represents mean ± SEM of two independent experiments with n = 3–5 per group per experiment. ∗∗∗p < 0.001 compared to control; ##p < 0.01 and ###p < 0.001 compared to BLM. BLM, Bleomycin.