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. 2018 Apr 25;22(3):301–309. doi: 10.4196/kjpp.2018.22.3.301

Fig. 4. Effect of atorvastatin pretreatment on neuroinflammation in KA-treated hippocampus.

Fig. 4

(A) Western blots show hippocampal COX-2 expression 24 h after KA treatment. Densitometric values of COX-2 expression from three separate experiments (n=6–7 mice per group) were normalized to β-actin levels. *p<0.05 vs. CTL. †p<0.05 vs. KA. (B) Representative images of immunostained COX-2 in the hippocampus of CTL, KA, KA+AS, and AS mice. The boxed area of each image is magnified in the lower panel. Scale bar=50 mm. (C) Western blots show hippocampal GFAP (C) and Iba-1 (D) expression 24 h after KA treatment. Densitometric values (n=6–7 mice per group) for GFAP and Iba1 were normalized to β-actin levels. *p<0.05 vs. CTL. †p<0.05 vs. KA-treated mice.