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. 2018 Mar 25;12(5):648–658. doi: 10.1002/1878-0261.12188

Table 2.

Univariate and multivariate analyses for OS prediction in validation cohort. HR, hazard ratio

Parameters Categories Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
Age (years) ≤ 61, > 61 1.335 (0.803–2.220) 0.265
Sex Male, female 0.586 (0.330–1.040) 0.068
Tumor size ≤ 3 cm, > 3 cm 3.071 (1.720–5.481) < 0.001 1.375 (0.725–2.607) 0.329
Lymph node metastasis Negative, positive 4.530 (2.570–7.983) < 0.001 1.638 (0.745–3.601) 0.220
TNM stage I, II, III 2.788 (1.961–3.966) < 0.001 1.859 (1.089–3.175) 0.023
SOX2OT expression Low, high 1.988 (1.187–3.330) 0.009 1.793 (1.040–3.093) 0.036
ANRIL expression Low, high 1.856 (1.108–3.109) 0.019 1.507 (0.874–2.598) 0.140