Table 5.
Immunohistochemistry analysis of signal transducer and activator of transcription 3 and phosphorylated signal transducer and activator of transcription 3 proteins expression in non‐small cell lung cancer samples
| Characteristics | STAT3 | χ2 | P‐value | pSTAT3 | χ2 | P‐value | ||
|---|---|---|---|---|---|---|---|---|
| (+) | (−) | (+) | (−) | |||||
| Gender | ||||||||
| Male | 15 | 11 | 0.120 | 0.729 | 12 | 14 | 0.742 | 0.389 |
| Female | 15 | 9 | 14 | 10 | ||||
| Age (years) | ||||||||
| ≤60 | 16 | 15 | 2.391 | 0.122 | 15 | 16 | 0.427 | 0.514 |
| >60 | 14 | 5 | 11 | 8 | ||||
| Histological type | ||||||||
| SCC | 15 | 6 | 1.970 | 0.160 | 12 | 9 | 0.384 | 0.536 |
| ADC | 15 | 14 | 14 | 15 | ||||
| Differentiation | ||||||||
| Well + moderate | 13 | 18 | 11.092 | 0.001 | 10 | 21 | 12.738 | 0.000 |
| Poor | 17 | 2 | 16 | 3 | ||||
| pTNM | ||||||||
| IA | 7 | 13 | 8.750 | 0.013 | 5 | 15 | 12.139 | 0.002 |
| IB | 15 | 5 | 12 | 8 | ||||
| II | 8 | 2 | 9 | 1 | ||||
| pSTAT3 | ||||||||
| Positive | 23 | 3 | 18.283 | 0.000 | — | — | — | — |
| Negative | 7 | 17 | ||||||
| MUC1 | ||||||||
| Positive | 18 | 1 | 15.407 | 0.000 | 14 | 5 | 5.773 | 0.016 |
| Negative | 12 | 19 | 12 | 19 | ||||
| Total | 30 | 20 | ‐ | ‐ | 26 | 24 | ‐ | ‐ |
ADC, adenocarcinoma; MUC1, mucin 1; NSCLC, non‐small cell lung cancer; pSTAT3, phosphorylated signal transducer and activator of transcription 3; pTNM, pathological TNM; SCC, squamous cell carcinoma; STAT3, signal transducer and activator of transcription 3.