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Weight gain, liver lipid content, and gene expression profile in AIBP-deficient mice fed a Western diet. Ldlr−/− and Apoa1bp−/−Ldlr−/− mice were fed a Western diet containing 1.25% cholesterol and 42% kcal from fat for 12 weeks starting from age 8 weeks. A: Mouse weights. B, C: Cholesterol content (B) and triglyceride content (C) in liver. D: Liver gene expression. Mean ± SEM; n = 12 or 13; *** P < 0.001; ** P < 0.01; * P < 0.05 (Student’s t-test).
