Skip to main content
. 2018 Mar 20;59(5):854–863. doi: 10.1194/jlr.M083618

Fig. 4.

Fig. 4.

Unchanged weight gain, hyperlipidemia, and atherosclerosis in AIBP-deficient mice fed a high-cholesterol, normal-fat diet. Ldlr−/− and Apoa1bp−/−Ldlr−/− mice were fed a 1% cholesterol, normal-fat diet for 16 weeks starting from age 8 weeks. A: Weight at the time of euthanization (n = 10; Student’s t-test). B–E: Plasma lipids at euthanization. Total cholesterol (B), cholesterol lipoprotein profile (C), total triglycerides (D), and triglyceride lipoprotein profile (E) (n = 10, Student’s t-test) are shown. F: En face atherosclerotic lesions (n = 10; Student’s t-test). G: Aortic root atherosclerotic lesion size as a function of distance from first leaflet appearance (n = 16; two-way ANOVA with Bonferroni’s post hoc test). H: Aortic root lesion volume (area under the curve from G; n = 16, Student’s t-test). Mean ± SEM; NS, not significant differences.