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. 2018 Apr 24;9:207. doi: 10.3389/fphar.2018.00207

Table 3.

Enrichment of identified genes in genome-wide association studies of human disease.

Gene set Number of genes in the set Number of overlapping genes P-value Adjusted P-value Overlapping genes
Type 1 diabetes and autoimmune thyroid diseases 23 3 4.4 × 10-9 4.8 × 10-6 HCP5, PRRC2A, TAP2
Fibrinogen 41 3 5.0 × 10-8 1.8 × 10-5 CPT1B, SLC22A4, SLC22A5
Ulcerative colitis 447 5 2.4 × 10-6 3.2 × 10-4 LSP1, SLC22A4, SLC22A5, TCF19, PRRC2A
Inflammatory bowel disease 719 5 3.5 × 10-5 2.2 × 10-3 LSP1, SLC22A4, SLC22A5, TCF19, PRRC2A
Obesity-related traits 745 4 4.6 × 10-4 1.2 × 10-2 IFI16, AIM2, ODF3B, S100P
Blood protein levels 914 4 1.2 × 10-3 2.4 × 10-2 HCP5, PRRC2A, TAP2, TAP2, PSMB8
Crohn’s disease 612 3 2.0 × 10-3 3.6 × 10-2 SLC22A4, SLC22A5, HLA-F