. 2017 Sep 27;187(5):982–991. doi: 10.1093/aje/kwx322

Table 4.

Associations Between Neighborhood Socioeconomic Status and Childhood Cancer Incidence, Registry-Based Case-Cohort Study (Total Sample = 14,854; Controls = 11,907), Linked Minnesota Birth and Cancer Records, 1989–2014

Model	All Childhood Cancers Combined (n = 2,947)			Acute Lymphoblastic Leukemia (n = 673)			Acute Myeloid Leukemia (n = 112)			Lymphomas (n = 311)			CNS Tumors (n = 662)
Model	OR	95% CI	P Value^a	OR	95% CI	P Value^a	OR	95% CI	P Value^a	OR	95% CI	P Value^a	OR	95% CI	P Value^a
1B^b	1.09	1.04, 1.14	<0.001	1.10	1.01, 1.20	0.03	1.07	0.88, 1.30	0.52	1.14	1.01, 1.30	0.04	1.18	1.08, 1.29	<0.001
2B^c	1.05	1.00, 1.11	0.04	1.08	0.99, 1.19	0.10	1.12	0.91, 1.39	0.30	1.15	1.00, 1.31	0.05	1.09	0.99, 1.20	0.09
3B^d	1.04	0.99, 1.09	0.12	1.07	0.97, 1.17	0.18	1.08	0.87, 1.33	0.50	1.14	0.99, 1.32	0.06	1.09	0.98, 1.20	0.10
4B^e	1.04	0.99, 1.09	0.16	1.06	0.97, 1.17	0.22	1.07	0.86, 1.33	0.54	1.15	1.00, 1.32	0.06	1.09	0.98, 1.20	0.11
5B^f	1.03	0.98, 1.09	0.21	1.05	0.96, 1.16	0.29	1.08	0.87, 1.34	0.49	1.13	0.98, 1.30	0.10	1.08	0.97, 1.19	0.15

	Neuroblastoma (n = 267)			Retinoblastoma (n = 80)			Wilms Tumor (n = 198)			Hepatoblastoma (n = 50)			Rhabdomyosarcoma (n = 79)
	OR	95% CI	P Value^a	OR	95% CI	P Value^a	OR	95% CI	P Value^a	OR	95% CI	P Value^a	OR	95% CI	P Value^a
1B^b	1.01	0.89, 1.15	0.82	1.07	0.85, 1.36	0.55	1.13	0.96, 1.32	0.14	0.83	0.66, 1.03	0.09	1.14	0.87, 1.50	0.34
2B^c	0.97	0.84, 1.11	0.67	1.16	0.90, 1.50	0.25	1.01	0.85, 1.20	0.90	0.86	0.67, 1.11	0.24	1.06	0.79, 1.42	0.71
3B^d	0.95	0.82, 1.09	0.45	1.17	0.90, 1.51	0.24	0.99	0.83, 1.18	0.92	0.84	0.65, 1.09	0.19	1.04	0.77, 1.41	0.80
4B^e	0.95	0.82, 1.09	0.43	1.16	0.90, 1.51	0.25	0.98	0.83, 1.17	0.85	0.88	0.68, 1.14	0.33	1.03	0.76, 1.40	0.83
5B^f	0.93	0.81, 1.08	0.35	1.13	0.87, 1.46	0.37	0.98	0.82, 1.17	0.83	0.92	0.70, 1.20	0.52	1.08	0.79, 1.48	0.63

Abbreviations: CI, confidence interval; CNS, central nervous system; OR, odds ratio.

^aP values estimated from a logistic mixed model with a random intercept for census tract clustering using a 2-sided hypothesis test.

^b Model 1B: bivariate.

^c Model 2B adjusted for maternal race/ethnicity.

^d Model 3B adjusted for maternal race/ethnicity, maternal age, birth order, birth year, and sex.

^e Model 4B adjusted for maternal race/ethnicity, maternal age, birth order, birth year, sex, birth weight, and gestational age.

^f Model 5B adjusted for maternal race/ethnicity, maternal age, birth order, birth year, sex, birth weight, gestational age, and maternal education.