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Induction of estrogenic activity with the three medicinal licorice extracts (G. inflata, green, filled triangles; G. glabra, brown, open diamonds; G. uralensis, blue, open hexagons). (A) ERα-dependent alkaline phosphatase activity induction in Ishikawa cells and (B) ERβ-ERE-luciferase assay in MDA-MB-231/β41 cells. The methods for the Ishikawa and ERE-luciferase assays are described in the Experimental Section. The data represent the means ± SEM of three independent determinations.
