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. 2018 Apr 24;9:848. doi: 10.3389/fimmu.2018.00848

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Copyright © 2018 Pouw, Gómez Delgado, López Lera, Rodríguez de Córdoba, Wouters, Kuijpers and Sánchez-Corral.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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FHR-3 levels are higher in patients with atypical hemolytic uremic syndrome (aHUS) than in controls. Histogram showing the mean FHR-3 levels in controls and in patients with aHUS with different CFHR3 genotypes. Statistically significant differences (Kruskal–Wallis test, p < 0.05) are denoted by an asterisk. Dashed lines indicate the highest FHR-3 level observed in controls and patients.